The Antibacterial Screening of Sineguelas Aso (Casearia grewiaefolia) Leaves Ethyl Acetate Extract

Abstract

Leaves ofsineguelas aso (Casearia grewiaefolia) were extracted using ethyl acetate, ethanol, water and hexane solvent. The extract was  screened against E. coli UPCC I195 and S. aureus UPCC 1143 using the agar cup method. The assay was conducted in three replicates. The solvent used was also screened against E. coli. The control used was tetracycline. Results showed that ethyl acetate extract manifested an average antimicrobial (Al) of 1.62 compared to the control i.e. tetracycline having an Al of2.0. However, ethyl acetate solventshowed an Al of0.9. All other extracts and solvents manifested zero clearing zone and zero antimicrobial indices.